Prime Medicine, Inc. (PRME) intrinsic value & 10-year financials

Prime Medicine, Inc. (PRME) has no Graham intrinsic value right now because the formula needs positive earnings. Over the last 7 fiscal years revenue shrank 2.3% a year to $4.6M, with an average return on invested capital of -130.9%.

Graham intrinsic value
—
Share price (Oct 17, 2026)
$3.47
Market cap
$516.2M
Revenue (FY2025)
$4.6M
Revenue growth (7-yr CAGR)
-2.3%
ROIC (10-yr avg)
-130.9%
Free cash flow (FY2025)
-$167.1M

PRME 10-year financial history

Fiscal year Revenue Net income EPS (diluted) Free cash flow Operating margin ROIC
FY2025 $4.6M -$201.1M -$1.35 -$167.1M -4498.1% -239.5%
FY2024 $3.0M -$195.9M -$1.65 -$130.2M -6787.4% -390.5%
FY2023 $0 -$198.1M -$2.18 -$174.1M — -169.3%
FY2022 $0 -$121.8M -$4.19 -$147.9M — 119.9%
FY2021 $0 -$165.4M -$14.19 -$38.2M — 24.9%
FY2020 $5.2M -$3.4M -$0.38 -$6.2M -17.9% —
FY2019 — — — — — —

Source: annual 10-K filings on SEC EDGAR. Figures in USD.

Executive summary

Prime Medicine, Inc. revenue growth over the past decade is N/A; insufficient history prevents a reliable 10-year CAGR calculation.

Prime Medicine, Inc. has earned high returns on invested capital, averaging 27.4% ROIC over the available history. High ROIC is consistent with a durable franchise, but it is not by itself proof of an economic moat.

Prime Medicine, Inc. capital allocation metrics are N/A for the decade; share count and net debt history are incomplete.

Benjamin Graham lens

Under Benjamin Graham's formula using SEC EDGAR fundamentals, Prime Medicine, Inc. is modeled at -2.3% normalized earnings growth with a 5.1% bond-yield adjustment. The resulting Graham intrinsic value estimate is $-4.50 per share.

PRME stock: frequently asked questions

What is the intrinsic value of Prime Medicine, Inc. (PRME) stock?

Graham's formula only works with positive earnings. Prime Medicine, Inc. reported diluted EPS of -$1.35 in fiscal 2025, so no Graham value is shown. The 10-year table shows revenue and cash-flow trends instead.

Does Prime Medicine, Inc. generate free cash flow?

Prime Medicine, Inc. generated -$167.1M of free cash flow (operating cash flow minus capital expenditures) in fiscal 2025. Free cash flow was positive in 0 of the last 6 reported years.

What is PRME's return on invested capital?

Average ROIC over the last 7 fiscal years was -130.9%, and average return on equity was 385.6%. Sustained ROIC above about 15% usually points to a durable competitive advantage.

Where does this PRME data come from?

From Prime Medicine, Inc.'s annual 10-K filings on SEC EDGAR, most recently filed Aug 6, 2026. Prices are end-of-day snapshots; valuations are formula outputs, not investment advice.

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