SYNLOGIC, Inc. (SYBX) intrinsic value & 10-year financials

SYNLOGIC, Inc. (SYBX) has a Graham intrinsic value of $4.86 per share. At $1.00 on Oct 17, 2026, the stock trades 79% below that value. Over the last 10 fiscal years revenue shrank 39.5% a year to $0, with an average return on invested capital of -68.8%.

Graham intrinsic value
$4.86
Share price (Oct 17, 2026)
$1.00
Price vs Graham value
79% below
Market cap
$12.3M
Revenue (FY2025)
$0
Revenue growth (10-yr CAGR)
-39.5%
ROIC (10-yr avg)
-68.8%
Free cash flow (FY2025)
-$4.4M

SYBX 10-year financial history

Fiscal year Revenue Net income EPS (diluted) Free cash flow Operating margin ROIC
FY2025 $0 -$1.0M -$0.08 -$4.4M — 65.6%
FY2024 $8.0K -$23.4M -$1.92 -$31.7M -511875.0% -326.6%
FY2023 $3.4M -$57.3M -$8.81 -$51.8M -1636.3% -96.7%
FY2022 $1.2M -$66.1M -$0.92 -$57.6M -5713.5% -58.3%
FY2021 $1.8M -$60.6M -$1.09 -$52.9M -3464.4% -48.4%
FY2020 $545.0K -$59.2M — -$39.9M -11094.7% -47.2%
FY2019 $2.2M -$51.4M — -$76.7M -2446.4% -40.8%
FY2018 $2.5M -$48.4M — -$48.1M -2032.9% -45.3%
FY2017 $2.4M -$40.4M — -$33.6M -1670.4% -55.5%
FY2016 $444.0K -$26.3M — -$26.5M -4721.6% -34.7%

Source: annual 10-K filings on SEC EDGAR. Figures in USD.

Executive summary

SYNLOGIC, INC. revenue growth over the past decade is N/A; insufficient history prevents a reliable 10-year CAGR calculation.

SYNLOGIC, INC. has historically struggled to out-earn its cost of capital, averaging just -36.5% ROIC.

SYNLOGIC, INC. capital allocation metrics are N/A for the decade; share count and net debt history are incomplete.

Benjamin Graham lens

Under Benjamin Graham's formula using SEC EDGAR fundamentals, SYNLOGIC, INC. is modeled at -39.5% normalized earnings growth with a 5.1% bond-yield adjustment. The resulting Graham intrinsic value estimate is $4.86 per share.

SYBX stock: frequently asked questions

What is the intrinsic value of SYNLOGIC, Inc. (SYBX) stock?

Using Benjamin Graham's revised formula, V = EPS × (8.5 + 2g) × 4.4 / Y, with reported diluted earnings per share, a -39.5% normalized growth rate (capped at 15%) and a 5.1% AAA corporate bond yield, SYBX's intrinsic value is about $4.86 per share.

Is SYBX stock undervalued?

At $1.00 (close on Oct 17, 2026), SYBX trades 79% below its Graham value of $4.86. On Graham's terms that leaves a margin of safety. A formula is a starting point for research, not a recommendation.

How fast has SYNLOGIC, Inc. grown?

Revenue went from $444.0K in fiscal 2016 to $0 in fiscal 2025, a compound annual growth rate of -39.5%. Net income was -$1.0M in fiscal 2025.

Does SYNLOGIC, Inc. generate free cash flow?

SYNLOGIC, Inc. generated -$4.4M of free cash flow (operating cash flow minus capital expenditures) in fiscal 2025. Free cash flow was positive in 0 of the last 10 reported years.

What is SYBX's return on invested capital?

Average ROIC over the last 10 fiscal years was -68.8%, and average return on equity was -51.3%. Sustained ROIC above about 15% usually points to a durable competitive advantage.

Where does this SYBX data come from?

From SYNLOGIC, Inc.'s annual 10-K filings on SEC EDGAR, most recently filed May 14, 2026. Prices are end-of-day snapshots; valuations are formula outputs, not investment advice.

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