Vertex Pharmaceuticals Inc. / Ma (VRTX) intrinsic value & 10-year financials

Vertex Pharmaceuticals Inc. / Ma (VRTX) has a Graham intrinsic value of $508.86 per share. At $499.74 on Oct 17, 2026, the stock trades 2% below that value. Over the last 10 fiscal years revenue grew 24.2% a year to $12.0B, with an average return on invested capital of 34.3%.

Graham intrinsic value
$508.86
Share price (Oct 17, 2026)
$499.74
Price vs Graham value
2% below
Market cap
$128.9B
Revenue (FY2025)
$12.0B
Revenue growth (10-yr CAGR)
24.2%
ROIC (10-yr avg)
34.3%
Free cash flow (FY2025)
$3.2B

VRTX 10-year financial history

Fiscal year Revenue Net income EPS (diluted) Free cash flow Operating margin ROIC
FY2025 $12.0B $4.0B $15.32 $3.2B 34.8% 24.5%
FY2024 $11.0B -$535.6M -$2.08 -$790.3M -2.1% -1.1%
FY2023 $9.9B $3.6B $13.89 $3.3B 38.8% 52.1%
FY2022 $8.9B $3.3B $12.82 $3.9B 48.2% 80.4%
FY2021 $7.6B $2.3B $9.01 $2.4B 36.7% 61.3%
FY2020 $6.2B $2.7B $10.29 $3.0B 46.0% 69.2%
FY2019 $4.2B $1.2B $4.51 $1.5B 28.8% 28.1%
FY2018 $3.0B $2.1B $8.09 $1.2B 20.8% 19.7%
FY2017 $2.5B $263.5M $1.04 $745.5M 5.0% 7.7%
FY2016 $1.7B -$112.1M -$0.46 $179.5M 0.6% 0.9%

Source: annual 10-K filings on SEC EDGAR. Figures in USD.

Executive summary

Vertex Pharmaceuticals is a consistent compounder, expanding top-line revenue at 24.2% annually over the past decade.

Vertex Pharmaceuticals has earned high returns on invested capital, averaging 34.3% ROIC over the available history. High ROIC is consistent with a durable franchise, but it is not by itself proof of an economic moat.

Vertex Pharmaceuticals has not shown aggressive share repurchases (>10% retirement) or a major balance-sheet leverage increase (>50% net debt growth) over the 10-year window.

Benjamin Graham lens

Under Benjamin Graham's formula using SEC EDGAR fundamentals, Vertex Pharmaceuticals is modeled at 15.0% normalized earnings growth with a 5.1% bond-yield adjustment. The resulting Graham intrinsic value estimate is $508.86 per share.

VRTX stock: frequently asked questions

What is the intrinsic value of Vertex Pharmaceuticals Inc. / Ma (VRTX) stock?

Using Benjamin Graham's revised formula, V = EPS × (8.5 + 2g) × 4.4 / Y, with reported diluted earnings per share, a 15.0% normalized growth rate (capped at 15%) and a 5.1% AAA corporate bond yield, VRTX's intrinsic value is about $508.86 per share.

Is VRTX stock undervalued?

At $499.74 (close on Oct 17, 2026), VRTX trades 2% below its Graham value of $508.86. On Graham's terms that leaves a margin of safety. A formula is a starting point for research, not a recommendation.

How fast has Vertex Pharmaceuticals Inc. / Ma grown?

Revenue went from $1.7B in fiscal 2016 to $12.0B in fiscal 2025, a compound annual growth rate of 24.2%. Net income was $4.0B in fiscal 2025.

Does Vertex Pharmaceuticals Inc. / Ma generate free cash flow?

Vertex Pharmaceuticals Inc. / Ma generated $3.2B of free cash flow (operating cash flow minus capital expenditures) in fiscal 2025. Free cash flow was positive in 9 of the last 10 reported years.

What is VRTX's return on invested capital?

Average ROIC over the last 10 fiscal years was 34.3%, and average return on equity was 22.6%. Sustained ROIC above about 15% usually points to a durable competitive advantage.

Where does this VRTX data come from?

From Vertex Pharmaceuticals Inc. / Ma's annual 10-K filings on SEC EDGAR. Prices are end-of-day snapshots; valuations are formula outputs, not investment advice.

Similar pharmaceutical preparations stocks