Protagonist Therapeutics, Inc. (PTGX) intrinsic value & 10-year financials

Protagonist Therapeutics, Inc. (PTGX) has a Graham intrinsic value of $89.41 per share. At $128.75 on Oct 17, 2026, the stock trades 44% above that value. Over the last 10 fiscal years revenue grew 10.9% a year to $46.0M, with an average return on invested capital of -56.6%.

Graham intrinsic value
$89.41
Share price (Oct 17, 2026)
$128.75
Price vs Graham value
44% above
Market cap
$8.2B
Revenue (FY2025)
$46.0M
Revenue growth (10-yr CAGR)
10.9%
ROIC (10-yr avg)
-56.6%
Free cash flow (FY2025)
$56.1M

PTGX 10-year financial history

Fiscal year Revenue Net income EPS (diluted) Free cash flow Operating margin ROIC
FY2025 $46.0M -$130.1M -$2.05 $56.1M -343.6% -29.2%
FY2024 $434.4M $275.2M $4.23 $182.8M 58.2% 42.3%
FY2023 $60.0M -$79.0M -$1.39 -$70.8M -156.1% —
FY2022 $26.6M -$127.4M -$2.60 -$108.9M -494.2% -96.9%
FY2021 $27.4M -$125.6M -$2.71 -$109.0M -460.0% -72.6%
FY2020 $28.6M -$66.2M -$1.92 -$73.0M -225.4% -56.2%
FY2019 $231.0K -$77.2M — -$42.5M -34857.6% -127.3%
FY2018 $30.9M -$38.9M — -$50.4M -136.7% —
FY2017 $20.1M -$37.0M — $3.2M -188.9% —
FY2016 — -$37.2M — -$30.4M — —

Source: annual 10-K filings on SEC EDGAR. Figures in USD.

Executive summary

Protagonist Therapeutics, Inc revenue growth over the past decade is N/A; insufficient history prevents a reliable 10-year CAGR calculation.

Protagonist Therapeutics, Inc has historically struggled to out-earn its cost of capital, averaging just -56.7% ROIC.

Protagonist Therapeutics, Inc capital allocation metrics are N/A for the decade; share count and net debt history are incomplete.

Benjamin Graham lens

Under Benjamin Graham's formula using SEC EDGAR fundamentals, Protagonist Therapeutics, Inc is modeled at 8.0% normalized earnings growth with a 5.1% bond-yield adjustment. The resulting Graham intrinsic value estimate is $89.41 per share.

PTGX stock: frequently asked questions

What is the intrinsic value of Protagonist Therapeutics, Inc. (PTGX) stock?

Using Benjamin Graham's revised formula, V = EPS × (8.5 + 2g) × 4.4 / Y, with reported diluted earnings per share, a 8.0% normalized growth rate (capped at 15%) and a 5.1% AAA corporate bond yield, PTGX's intrinsic value is about $89.41 per share.

Is PTGX stock undervalued?

At $128.75 (close on Oct 17, 2026), PTGX trades 44% above its Graham value of $89.41. On Graham's terms the shares look fully priced. A formula is a starting point for research, not a recommendation.

Does Protagonist Therapeutics, Inc. generate free cash flow?

Protagonist Therapeutics, Inc. generated $56.1M of free cash flow (operating cash flow minus capital expenditures) in fiscal 2025. Free cash flow was positive in 3 of the last 10 reported years.

What is PTGX's return on invested capital?

Average ROIC over the last 10 fiscal years was -56.6%, and average return on equity was -31.6%. Sustained ROIC above about 15% usually points to a durable competitive advantage.

Where does this PTGX data come from?

From Protagonist Therapeutics, Inc.'s annual 10-K filings on SEC EDGAR, most recently filed Aug 5, 2026. Prices are end-of-day snapshots; valuations are formula outputs, not investment advice.

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